Effects of a binge drinking history or an acute episode on the stress response in adolescents: an experimental gender perspective
DOI:
https://doi.org/10.20882/adicciones.2015Palabras clave:
consumo intensivo de alcohol, alcohol, respuesta al estrés, adolescentes, géneroResumen
Adolescence is a period of vulnerability to alcohol binge drinking (BD), being this consumption pattern very common among adolescents and young adults. Furthermore, there is a lack of experimental studies evaluating the effects of alcohol in adolescent population of both sexes. The aim of this study was to evaluate the effects of having a binge drinking (BD) consumption history and/or an acute BD episode on the stress response in male and female adolescents. Participants were 150 adolescents (75 females and 75 males). According to their drinking pattern, subjects were assigned to one of three experimental conditions in each sex: Refrainers-Control (R-Co), Binge Drinkers-Control (BD-Co) or Binge Drinkers-Alcohol (BD-A). After treatment, their stress response was measured throughout the following parameters: cortisol, systolic and diastolic blood pressure (SBP and DBP), heart rate (HR) and perceived stress (PS). A decrease of cortisol levels over time was observed in the present study. Also, the experimental condition was significant for HR, showing the BD-A group higher HR than any other group. Regardless of the experimental condition, sex differences were evident in several measures, males showing higher cortisol levels and higher SBP than females, while females obtaining higher PS scores than males. In conclusion, both the decrease of cortisol levels over time and the gender differences in cortisol, SPB and PS strengthen our previous results, using gender as an experimental variable. Furthermore, an acute BD episode in binge drinkers increases HR without affecting the other stress variables, providing a new finding in this field of research.Citas
Allen, C. D., Lee, S., Koob, G. F. y Rivier, C. (2011). Immediate and prolonged effects of alcohol exposure on the activity of the hypothalamic-pituitary-adrenal axis in adult and adolescent rats. Brain, Behavior, and Immunity, 25 (Suppl 1), S50–60. https://doi.org/10.1016/j.bbi.2011.01.016
Anbumalar, C., Dorathy, A. P., Jaswanti, V. P., Priya, D. y Reniangelin, D. (2017). Gender differences in perceived stress levels and coping strategies among college students. The International Journal of Indian Psychology, 4, 22–33. https://doi.org/10.25215/0404.103
Antón-Toro, L. F., Bruña R, Suárez-Méndez, I., Correas, A., García-Moreno, L. M. y Maestú, F. (2021). Abnormal organization of inhibitory control functional networks in future binge drinkers. Drug Alcohol Dependence, 218, 108401. https://doi.org/10.1016/j.drugalcdep.2020.108401
Bau, P. F., Moraes, R. S., Bau, C. H., Ferlin, E. L., Rosito, G. A. y Fuchs, F. D. (2011). Acute ingestion of alcohol and cardiac autonomic modulation in healthy volunteers. Alcohol, 45, 123–129. https://doi.org/10.1016/j.alcohol.2010.08.011
Blaine, S. K. y Sinha, R. (2017). Alcohol, stress, and glucocorticoids: From risk to dependence and relapse in alcohol use disorders. Neuropharmacology, 122, 136–147. https://doi.org/10.1016/j.neuropharm.2017.01.037
Chu, B., Marwaha, K., Sanvictores, T. y Ayers, D. (2021). Physiology, stress reaction. En StatPearls. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK541120/
Chung, T., Creswell, K. G., Bachrach, R., Clark, D. B. y Martin, C. S. (2018). Adolescent Binge Drinking. Alcohol Research, 39, 5–15.
Cohen, S., Kamarck, T. y Mermelstein, R. (1983). A global measure of perceived stress. Journal of Health and Social Behavior, 24, 385–396. https://doi.org/10.2307/2136404
Cortez, I., Rodgers, S. P., Kosten, T. A. y Leasure, J. L. (2020). Sex and age effects on neurobehavioral toxicity induced by binge alcohol. Brain Plasticity, 6, 5–25. https://doi.org/10.3233/BPL-190094
Dedovic, K., Duchesne, A., Andrews, J., Engert, V. y Pruessner, J.C. (2009). The brain and the stress axis: The neural correlates of cortisol regulation in response to stress. Neuroimage, 47, 864–71. https://doi.org/10.1016/j.neuroimage.2009.05.074
Fogelman, N. y Canli, T. (2018). Early life stress and cortisol: A meta-analysis. Hormones and Behavior, 98, 63–76. https://doi.org/10.1016/j.yhbeh.2017.12.014
Hagan, M. J., Modecki, K., Tan, L. M., Luecken, L., Wolchik, S. y Sandler, I. (2019). Binge drinking in adolescence predicts an atypical cortisol stress response in young adulthood. Psychoneuroendocrinology, 100, 137–144. https://doi.org/10.1016/j.psyneuen.2018.10.002
IBM Corp Released. (2021). IBM SPSS Statistics for Windows, Version 28.0. Armonk, New York: IBM Corp.
Jones, S. A. y Nagel, B. J. (2019). Altered frontostriatal white matter microstructure is associated with familial alcoholism and future binge drinking in adolescence. Neuropsychopharmacology, 44, 1076–1083. https://doi.org/10.1038/s41386-019-0315-x
Joyner, M. J., Wallin, B. G. y Charkoudian, N. (2016). Sex differences and blood pressure regulation in humans. Experimental Physiology, 101, 349–355. https://doi.org/10.1113/EP085146
Kobayashi, H., Song, C., Ikei, H., Park, B. J., Kagawa, T. y Miyazaki, Y. (2017). Diurnal changes in distribution characteristics of salivary cortisol and immunoglobulin A concentrations. International Journal of Environmental Research and Public Health,14, 987. https://doi.org/10.3390/ijerph14090987
Kudielka, B. M., Hellhammer, D. H. y Wüst, S. (2009). Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge. Psychoneuroendocrinology, 34, 2–18. https://doi.org/10.1016/j.psyneuen.2008.10.004
Lee, S. K. (2018). Sex as an important biological variable in biomedical research. BMB Reports, 51, 167–173. https://doi.org/10.5483/bmbrep.2018.51.4.034
Lees, B., Meredith, L. R., Kirkland, A. E., Bryant, B. E. y Squeglia, L. M. (2020). Effect of alcohol use on the adolescent brain and behavior. Pharmacology Biochemistry and Behavior, 192, 172906. https://doi.org/10.1016/j.pbb.2020.172906
López-Caneda, E., Mota, N., Crego, A., Velasquez, T., Corral, M., Rodríguez Holguín, S. y Cadaveira, F. (2014). Neurocognitive anomalies associated with the binge drinking pattern of alcohol consumption in adolescents and young people: A review. Adicciones, 26, 334–359. https://doi.org/10.20882/adicciones.39
McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Reviews, 87, 873–904. https://doi.org/10.1152/physrev.00041.2006
Michou, M., Panagiotakos, D. B., Lionis, C. y Costarelli, V. (2021). Low health literacy and perceived stress in adults: is there a link? Central European Journal of Public Health, 29, 195–200. https://doi.org/10.21101/cejph.a6692
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (2004). The National Institute on Alcohol Abuse and Alcoholism council aproves definition of binge drinking. NIAAA Newsletter, 3, 3.
Observatorio Español de las Drogas y las Adicciones (OEDA) (2021). Encuesta sobre Uso de Drogas en Enseñanzas Secundarias en España (ESTUDES) 1994-2021. Madrid: Ministerio de Sanidad, Consumo y Bienestar Social.
Parada, M., Corral, M., Caamaño-Isorna, F., Mota, N., Crego, A., Rodríguez Holguín, S. y Cadaveira, F. (2011). Definición del concepto de consumo intensivo de alcohol adolescente (binge drinking). Adicciones, 23, 53-63. https://doi.org/10.20882/adicciones.167
Petit, G., Maurage, P., Kornreich, C., Verbanck, P. y Campanella, S. (2014). Binge drinking in adolescents: A review of neurophysiological and neuroimaging research. Alcohol & Alcoholism, 49, 198–206. https://doi.org/10.1093/alcalc/agt172
Price, J. L., Frazier, I. R., Lewis, B., Walker, R., Javors, M. A., Nixon, S. J. y Adinoff, B. (2019). Differences in pituitary-adrenal reactivity in black and white men with and without alcohol use disorder. Psychoneuroendocrinology, 100, 180–189. https://doi.org/10.1016/j.psyneuen.2018.10.004
Ramírez-Piña, M., Monleón, S. y Vinader-Caerols, C. (2021). Hypothalamic-pituitary-adrenal axis dysregulationinitiated by a binge drinking pattern, but not by acute alcohol intake, in female and male adolescents. Adicciones, 35, 421–432. https://doi.org/10.20882/adicciones.1665
Saunders, J. B., Aasland, O. G., Babor, T. F., de La Fuente, J. R. y Grant, M. (1993). Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-II. Addiction, 88, 791–804. https://doi.org/10.1111/j.1360-0443.1993.tb02093.x
Ulrich-Lai, Y. M. y Herman, J. P. (2009). Neural regulation of endocrine and autonomic stress responses. Nature Reviews Neuroscience, 10, 397–409. https://doi.org/10.1038/nrn2647
Vinader-Caerols, C. y Monleón, S. (2019). Binge drinking and memory in adolescents and young adults. En S. Palermo y M. Bartoli (Eds.), Inhibitory Control Training-A Multidisciplinary Approach (pp.1–19). IntechOpen. http://dx.doi.org/10.5772/intechopen.88485
Vinader-Caerols, C. y Monleón, S. (2021). Binge drinking, alone or with cannabis, during adolescence triggers different effects on immediate visual memory in men and women. Frontiers in Psychiatry, 12, 797221. https://doi.org/10.3389/fpsyt.2021.797221
Vinader-Caerols, C., Monleón, S., Carrasco, C. y Parra, A. (2012). Effects of alcohol, coffee, and tobacco, alone or in combination, on physiological parameters and anxiety in a young population. Journal of Caffeine Research, 2, 70–76. https://doi.org/10.1089/jcr.2012.0018
Vinader-Caerols, C., Talk, A., Montañés, A., Duque, A. y Monleón, S. (2017a). Differential effects of alcohol on memory performance in adolescent men and women with a binge drinking history. Alcohol and Alcoholism, 52, 610–616. https://doi.org/10.1093/alcalc/agx040
Vinader-Caerols, C., Duque, A., Montañés, A. y Monleón, S. (2017b). Blood alcohol concentration-related lower performance in immediate visual memory and working memory in adolescent binge drinkers. Frontiers in Psychology, 8, 1720. https://doi.org/10.3389/fpsyg.2017.01720
Weera, M. M. y Gilpin, N. W. (2019). Biobehavioral interactions between stress and alcohol. Alcohol Research: Current Reviews, 40, 04. https://doi.org/10.35946/arcr.v40.1.04
